The Department of Health Sciences and Medicine is made up of three close-knit sections: Health Sciences and Health Policy, Medicine and Rehabilitation. The new department was created on 1 August 2019 as a result of the Faculty of Humanities and Social Sciences’ Department of Health Sciences and Health Policy restructure. It reports directly to the rector.

The Health Sciences and Health Policy section focuses on research into what is known as functioning health and addresses the best way to organise the health system at all levels. The department offers a Master in Health Sciences (MSc), a doctoral programme and a post-doctoral programme. The section heads up an inter-university research platform, the “Swiss Learning Health System”, which is supported by swissuniversities, the rectors' conference for all universities.

The Medicine section deals with the diagnosis and treatment of illnesses within the scope of clinical sciences and also covers the optimum provision of clinical services. The section offers a Joint Medical Master in cooperation with the University of Zurich. Students are trained by clinical partners in Central Switzerland, including the Luzerner Kantonsspital (LUKS), Luzerner Psychiatrie, the Institute of Primary and Community Care, the Swiss Paraplegic Centre (SPC) and the Hirslanden Klinik St. Anna. The department also offers a further education programme called “CAS Palliative Care” in close cooperation with the Luzerner Kantonsspital. In the field of research, the section runs a clinical trial unit (CTU) in cooperation with the SPC and LUKS. The CTU is a scientific platform with standardised processes for conducting clinical trials in accordance with ethical and scientific criteria.

The Rehabilitation section focuses on the best way to organise the health, social and employment systems with the aim of optimising human functioning in the event of illness, after an accident or during old age. In this section, the department works in close cooperation with the Swiss Paraplegic Centre in Nottwil, the only non-university research institution in Central Switzerland. The section’s scientific activities are coordinated in the new Center for Rehabilitation in Global Health Systems, which has also been a World Health Organisation cooperation centre since 2019.

The department forms the academic centre of a network which has health sector partners across the canton of Lucerne. These include Swiss Paraplegic Research and the Swiss Paraplegic Centre in Nottwil, the Luzerner Kantonsspital, Luzerner Psychiatrie, the Institute of Primary and Community Care and the Hirslanden Klinik St. Anna. On an international level, the department works with partners such as the World Health Organisation.